C50H58N7O9P
932 g/mol
Pharmaceutical IntermediateWarning
2'-O-MOE-N6-Benzoyl-Adenosine Phosphoramidite
CAS251647-53-7EC804-906-4
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate
This compound is a protected nucleoside phosphoramidite building block used in the synthesis of oligonucleotides. It features a 2'-O-(2-methoxyethyl) modification, an N6-benzoyl protected adenine base, and a dimethoxytrityl protecting group.
Nucleoside phosphoramidite building block for oligonucleotide synthesisPharmaceutical intermediate for nucleic acid-based research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 251647-53-7
Related Compounds
StrongStructure SimilarSimilarity 0.91
N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS110782-31-5
pharmaceutical intermediate
StrongStructure SimilarSimilarity 0.90
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CAS171486-59-2
research compound
StrongStructure SimilarSimilarity 0.89
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(hexadecyloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CAS2382942-35-8
pharmaceutical intermediate
StrongStructure SimilarSimilarity 0.87
N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS104992-55-4
pharmaceutical intermediate
ApplicationSame Use
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine
CAS81265-93-2
pharmaceutical intermediate
ApplicationSame Use
DMF-dG Phosphoramidite
CAS330628-04-1
pharmaceutical intermediate
ApplicationSame Use
(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate
CAS1120329-61-4
pharmaceutical intermediate
ReferenceSame Category
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS251647-55-9
pharmaceutical intermediate
Safety Reference
Warning
H302Harmful if swallowed
Identifiers
IUPAC Name
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChIKey
VPBYBQBHLYRLHG-HDMAWCRFSA-N
SMILES
CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
Synonyms (14)
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