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Home/Compounds/Pharmaceutical Intermediate/N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
C53H66N7O8PSi
988.2 g/mol
Pharmaceutical Intermediate

Bz-rA Phosphoramidite

CAS104992-55-4
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite intermediate used in the synthesis of oligonucleotides. It features a heavily functionalized, flexible molecular structure with high lipophilicity and multiple aromatic rings.

Phosphoramidite intermediate for oligonucleotide synthesisResearch reagent for nucleic acid chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 104992-55-4

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Related Compounds

StrongStructure SimilarSimilarity 0.96

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS129451-75-8

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.89

N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS110782-31-5

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.87

2'-O-MOE-N6-Benzoyl-Adenosine Phosphoramidite

CAS251647-53-7

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.86

N6-Me-rA phosphoramidite

CAS588698-79-7

research compound

ReferenceSame Category

Diethyl 1,3-acetonedicarboxylate

CAS105-50-0

pharmaceutical intermediate

ReferenceSame Category

Diethyl malonate

CAS105-53-3

pharmaceutical intermediate

ReferenceSame Category

Ethyl cyanoacetate

CAS105-56-6

pharmaceutical intermediate

ReferenceSame Category

4-Methoxymandelic acid

CAS10502-44-0

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide

InChIKey

FFXHNCNNHASXCT-RFMFGJHUSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

Synonyms (21)
  • Bz-rA Phosphoramidite
  • DMT-2'O-TBDMS-rA(bz) amidite