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Home/Compounds/Pharmaceutical Intermediate/N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
C48H54N7O8P
888 g/mol
Pharmaceutical Intermediate

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

CAS110782-31-5EC892-124-4
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite monomer used in the synthesis of oligonucleotides. It features a complex structure with multiple aromatic rings, ether groups, and a nitrile group, making it a specialized reagent for solid-phase DNA/RNA synthesis.

Phosphoramidite monomer for oligonucleotide synthesisIntermediate for pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

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Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

InChIKey

AZCGOTUYEPXHMJ-PSVHYZMASA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

Synonyms (29)
  • 2'-OMe-A(Bz) Phosphoramidite
  • 2'-OMe-Bz-A Phosphoramidite
  • Cytidine Impurity 53
  • Dmt-2'-O-me-ra(bz) amidite