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Home/Compounds/Pharmaceutical Intermediate/(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate
C51H60N7O10P
962 g/mol
Pharmaceutical Intermediate

(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate

CAS1120329-61-4
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

This compound is a nucleoside phosphoramidite building block used in the synthesis of oligonucleotides. It is a protected, functionalized intermediate designed for automated DNA/RNA synthesis in research and pharmaceutical manufacturing.

oligonucleotide synthesispharmaceutical intermediate for nucleic acid-based drug developmentlaboratory reagent for chemical biology studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.75

(2R)-2-(6-Benzamido-9H-purin-9-yl)-2-(((2R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)ethyl benzoate

CAS1120329-52-3

research compound

SimilarStructure SimilarSimilarity 0.73

(S)-GNA-G(iBu) phosphoramidite

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2'-O-MOE-N6-Benzoyl-Adenosine Phosphoramidite

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DMF-dG Phosphoramidite

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N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine

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ReferenceSame Category

Oxolan-3-yl 4-methylbenzene-1-sulfonate

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ReferenceSame Category

(S)-(-)-2-(Diphenylhydroxymethyl)pyrrolidine

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ReferenceSame Category

3-Hydroxy-4-methylpyridine

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Identifiers
IUPAC Name

[(2R)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxy-2-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]ethyl] benzoate

InChIKey

PCZJDFIZVYBABW-WESQYFQMSA-N

SMILES

CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@@H](COC(=O)C3=CC=CC=C3)O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)COP(N(C(C)C)C(C)C)OCCC#N

Synonyms (4)
  • UNA 2'-OBz G(iBu) amidite
  • UNA-G(iBu)-CE Phosphoramidite

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