(S)-GNA-G(iBu) phosphoramidite is a protected glyceryl nucleic acid building block used as a pharmaceutical intermediate in the custom synthesis of oligonucleotides. Its structure includes a dimethyltrityl (DMT) protecting group, a phosphoramidite group for automated coupling, and an N-isobutyryl (iBu)-protected guanine base.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 182625-68-9
(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate
pharmaceutical intermediate
(S)-GNA-A(Bz)-phosphoramidite
pharmaceutical intermediate
(S)-GNA-C(Bz)-phosphoramidite
pharmaceutical intermediate
Guanosine, 3′-O-(2-methoxyethyl)-
pharmaceutical intermediate
1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole
pharmaceutical intermediate
4-chloro-3-iodopyridine-2-carbonitrile
pharmaceutical intermediate
4-Iodobenzyl alcohol
pharmaceutical intermediate
Dimethyl 1,3-acetonedicarboxylate
pharmaceutical intermediate
N-[9-[(2S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
GOUPKQZMFOWLOW-AUNMUFMCSA-N
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C[C@@H](COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N