This compound is a phosphoramidite monomer used as a pharmaceutical intermediate in the production of oligonucleotides. It features a protected adenine base and a dimethoxytrityl protecting group, with stereochemistry specified at the glycerol backbone.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 851050-24-3
(2R)-2-(6-Benzamido-9H-purin-9-yl)-2-(((2R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)ethyl benzoate
research compound
(S)-GNA-C(Bz)-phosphoramidite
pharmaceutical intermediate
(S)-GNA-G(iBu) phosphoramidite
pharmaceutical intermediate
4-Methoxytriphenylmethyl chloride
pharmaceutical intermediate
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine
pharmaceutical intermediate
3-[(1R)-1-(Dimethylamino)ethyl]phenol
pharmaceutical intermediate
2,5-Difluorobenzyl bromide
pharmaceutical intermediate
3-Chloro-2,5-difluoropyridine
pharmaceutical intermediate
N-[9-[(2S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]purin-6-yl]benzamide
RHPZFMWWZNRHHT-MXHUVDEASA-N
CC(C)N(C(C)C)P(OCCC#N)O[C@@H](CN1C=NC2=C(N=CN=C21)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC