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Home/Compounds/Pharmaceutical Intermediate/(S)-GNA-C(Bz)-phosphoramidite
C44H50N5O7P
791.9 g/mol
Pharmaceutical Intermediate

(S)-GNA-C(Bz)-phosphoramidite

CAS885322-06-5
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a protected phosphoramidite monomer used as a building block in oligonucleotide synthesis. It features a (S)-GNA backbone with a benzoyl-protected cytosine nucleobase and acid-labile dimethoxytrityl (DMT) protecting group.

Chemical intermediate for oligonucleotide manufacturingLaboratory reagent for nucleic acid research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.89

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Identifiers
IUPAC Name

N-[1-[(2S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-2-oxopyrimidin-4-yl]benzamide

InChIKey

IQSXGILXOHYNMA-CIMWKYAKSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H](CN1C=CC(=NC1=O)NC(=O)C2=CC=CC=C2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Synonyms (3)
  • (S)-GNA-C(Bz)-phosphoramidite