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Home/Compounds/Pharmaceutical Intermediate/[[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]methyl]triphenylphosphonium bromide
C34H34BrFN3O2PS
678.6 g/mol
Pharmaceutical Intermediate

((4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)methyl)triphenylphosphonium bromide

CAS885477-83-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a phosphonium salt used as an intermediate in the manufacturing of rosuvastatin, a statin medication. It features a pyrimidine ring with fluorophenyl and isopropyl substituents, along a triphenylphosphonium group.

Pharmaceutical intermediate for rosuvastatin synthesisLaboratory reagent for statin intermediate research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ApplicationSame Use

(5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-3-oxo-6-heptenoic acid ethyl ester

CAS901765-36-4

pharmaceutical intermediate

ReferenceSame Category

6-Bromo-4-indazolecarboxylic acid methyl ester

CAS885518-49-0

pharmaceutical intermediate

ReferenceSame Category

4-Bromo-3-iodo-1H-indazole

CAS885521-72-2

pharmaceutical intermediate

ReferenceSame Category

2-Bromo-5-fluoropyridine-4-carboxylic acid

CAS885588-12-5

pharmaceutical intermediate

ReferenceSame Category

N-Cbz-2-Phosphonoglycine trimethyl ester

CAS88568-95-0

pharmaceutical intermediate

Identifiers
IUPAC Name

[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]methyl-triphenylphosphanium bromide

InChIKey

GGEHQGAHLWFTET-UHFFFAOYSA-M

SMILES

CC(C)C1=NC(=NC(=C1C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC=C(C=C5)F)N(C)S(=O)(=O)C.[Br-]

Synonyms (9)

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