ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/DMF-dG Phosphoramidite
C43H53N8O7P
824.9 g/mol
Pharmaceutical Intermediate

DMF-dG Phosphoramidite

CAS330628-04-1
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

DMF-dG Phosphoramidite is a chemically modified nucleoside building block used in the solid-phase synthesis of oligonucleotides. Its structure incorporates a protected deoxyguanosine base with a dimethylformamidine (DMF) protecting group, a dimethoxytrityl (DMT) group on the 5'-hydroxyl, and a phosphoramidite moiety on the 3'-hydroxyl, enabling automated DNA synthesis.

Nucleoside phosphoramidite building block for oligonucleotide synthesisPharmaceutical intermediate for nucleic acid-based research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 330628-04-1

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

StrongStructure SimilarSimilarity 0.86

3'-DMTr-dG(dmf)

CAS261728-23-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

(2R,4S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1H-purin-9(6H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS1391913-24-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.79

(Z)-N'-{9-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)oxolan-2-yl]-9H-purin-6-yl}-N,N-dimethylmethanimidamide

CAS154656-78-7

research compound

SimilarStructure SimilarSimilarity 0.77

DMT-2'-O-TBDMS-G(dmf)-CE-phosphoramidite

CAS149559-87-5

research compound

ApplicationSame Use

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine

CAS81265-93-2

pharmaceutical intermediate

ApplicationSame Use

(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate

CAS1120329-61-4

pharmaceutical intermediate

ApplicationSame Use

2'-O-MOE-N6-Benzoyl-Adenosine Phosphoramidite

CAS251647-53-7

pharmaceutical intermediate

ReferenceSame Category

4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester

CAS330785-81-4

pharmaceutical intermediate

Identifiers
IUPAC Name

N'-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChIKey

YRQAXTCBMPFGAN-UNHDIWNRSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=C(NC6=O)/N=C/N(C)C

Synonyms (8)
  • DMF-dG Phosphoramidite
  • DMT-dG(dmf) Phosphoramidite
  • Dmt-dg(dmf) amidite