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Home/Compounds/Pharmaceutical Intermediate/3'-DMTr-dG(dmf)
C43H53N8O7P
824.9 g/mol
Pharmaceutical Intermediate

3'-DMTr-dG(dmf)

CAS261728-23-8
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

3'-DMTr-dG(dmf) is a modified nucleoside phosphoramidite used as a building block in automated DNA synthesis. Its structure includes a protected guanine base with a dimethylformamidine group and a dimethoxytrityl protecting group, enabling controlled oligonucleotide chain assembly.

DNA synthesis phosphoramidite building blockresearch reagent for oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.86

DMF-dG Phosphoramidite

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Identifiers
IUPAC Name

N'-[9-[(2R,4S,5R)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-5-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]oxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChIKey

IUJKDDDBKLNXIF-UNHDIWNRSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)OC[C@@H]1[C@H](C[C@@H](O1)N2C=NC3=C2N=C(NC3=O)/N=C/N(C)C)OC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

Synonyms (3)
  • 3'-DMTr-dG(dmf)