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Home/Compounds/Pharmaceutical Intermediate/DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite
C50H67N4O8PSi
911.1 g/mol
Pharmaceutical Intermediate

DMTr-5-Ethynyl-TIPS-dU-3'-CE-Phosphoramidite

CAS1472616-97-9
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite building block used in DNA synthesis. It features a protected ethynyl group and a dimethoxytrityl (DMTr) protecting group, suitable for automated oligonucleotide assembly.

DNA synthesis phosphoramidite building blockLaboratory reagent for oligonucleotide research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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SimilarStructure SimilarSimilarity 0.80

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Identifiers
IUPAC Name

3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-[2,4-dioxo-5-[2-tri(propan-2-yl)silylethynyl]pyrimidin-1-yl]oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

CCVQXLLQYFTKGP-KSJPBEHZSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C#C[Si](C(C)C)(C(C)C)C(C)C

Synonyms (2)

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