C10H17NO5
231.25 g/mol
Pharmaceutical IntermediateWarning
N-Boc-4-hydroxy-D-proline, trans-
CAS147266-92-0EC959-006-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
N-Boc-4-hydroxy-D-proline, trans- is a chiral, protected amino acid derivative used as an intermediate in peptide synthesis. Its structure features a tert-butoxycarbonyl (Boc) protecting group on the pyrrolidine nitrogen and a trans-configured hydroxyl group, making it suitable for incorporating modified proline residues into synthetic peptides.
Peptide synthesis intermediateBuilding block for pharmaceutical research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 147266-92-0
Related Compounds
SimilarStructure SimilarSimilarity 0.74
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ReferenceSame Category
(R)-2-(Boc-amino)pentane-1,5-diyl Dimethanesulfonate
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Safety Reference
Warning
H319Causes serious eye irritation
H315Causes skin irritation
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name
(2R,4S)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
InChIKey
BENKAPCDIOILGV-NKWVEPMBSA-N
SMILES
CC(C)(C)OC(=O)N1C[C@H](C[C@@H]1C(=O)O)O
Synonyms (19)
- BOC-D-HYP-OH
- Boc-trans-D-Hyp-OH
- Ertapenem Impurity C28