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Home/Compounds/Pharmaceutical Intermediate/N-Boc-N'-tosyl-L-arginine
C18H28N4O6S
428.5 g/mol
Pharmaceutical Intermediate

L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-

CAS13836-37-8EC237-549-2
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected arginine derivative used as an intermediate in solid-phase peptide synthesis. Its structure incorporates a tert-butoxycarbonyl (Boc) protecting group on the amino function and a tosyl (Tos) group on the guanidino side chain, enabling selective deprotection during peptide chain assembly.

Peptide synthesis intermediateBuilding block for incorporating arginine residues in solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(2S)-5-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid

InChIKey

WBIIPXYJAMICNU-AWEZNQCLSA-N

SMILES

CC1=CC=C(C=C1)S(=O)(=O)NC(=NCCC[C@@H](C(=O)O)NC(=O)OC(C)(C)C)N

Synonyms (16)
  • BOC-Nomega -tosyl-L-arginine
  • Boc-Arg(Tos)
  • Boc-Arg(Tos)-OH
  • Boc-Arg(Ts)

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