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Home/Compounds/Pharmaceutical Intermediate/Fmoc-His-Aib-OH
C25H26N4O5
462.5 g/mol
Pharmaceutical Intermediate

Fmoc-His-Aib-OH

CAS1446013-07-5
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Fmoc-His-Aib-OH is a protected dipeptide building block used in solid-phase peptide synthesis. It consists of an N-terminal Fmoc-protected histidine linked to an alpha-methylalanine (Aib) residue, which introduces conformational constraints into peptide sequences.

Peptide synthesis intermediateBuilding block for constrained peptide analogs

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-2-methylpropanoic acid

InChIKey

DRXNKOXLDLFGEG-NRFANRHFSA-N

SMILES

CC(C)(C(=O)O)NC(=O)[C@H](CC1=CN=CN1)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Synonyms (5)
  • Fmoc-His-Aib-OH
  • Fmoc-His-Aib-OH, TFA salt
  • Semaglutide impurity 103

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