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Home/Compounds/Pharmaceutical Intermediate/N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine
C44H49N5O7Si
788 g/mol
Pharmaceutical Intermediate

N-Benzoyl-5'-O-(bis(4-methoxyphenyl)(phenyl)methyl)-2'-O-(tert-butyl(dimethyl)silyl)adenosine

CAS81265-93-2
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside derivative used as a building block in oligonucleotide synthesis. Its structure includes a purine base, a sugar moiety with silyl and trityl protecting groups, and multiple aromatic rings, making it suitable for automated DNA/RNA synthesis.

nucleoside phosphoramidite building block for oligonucleotide synthesisintermediate in the production of modified nucleic acids

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.86

N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

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pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.82

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine

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SimilarStructure SimilarSimilarity 0.79

DMT-2'-F-Bz-dA

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2'-O-MOE-N6-Benzoyl-Adenosine Phosphoramidite

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(2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-3H-purin-9(6H)-yl)ethyl benzoate

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DMF-dG Phosphoramidite

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pharmaceutical intermediate

ReferenceSame Category

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine

CAS81279-39-2

pharmaceutical intermediate

ReferenceSame Category

N-[(1,1-Dimethylethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-D-alanine

CAS81306-93-6

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide

InChIKey

DAZIGOPASNJPCJ-GNECSJIWSA-N

SMILES

CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

Synonyms (12)
  • TBS-Bz-rA