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Home/Compounds/Pharmaceutical Intermediate/N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
C39H37N5O7
687.7 g/mol
Pharmaceutical Intermediate

N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

CAS110764-72-2
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside intermediate used in oligonucleotide synthesis. It features a purine base with a benzamide group and a dimethoxytrityl (DMT) protecting group, along with multiple ether and aromatic ring functionalities.

Nucleoside intermediate for oligonucleotide synthesisPharmaceutical intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.88

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine

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StrongStructure SimilarSimilarity 0.86

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine

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pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.84

DMT-2'-F-Bz-dA

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research compound

SimilarStructure SimilarSimilarity 0.73

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

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pharmaceutical intermediate

ApplicationSame Use

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methylcytidine

CAS199593-08-3

pharmaceutical intermediate

ApplicationSame Use

N-(1-((1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

CAS445012-77-1

pharmaceutical intermediate

ReferenceSame Category

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-O-methylcytidine

CAS110764-78-8

Oligonucleotide synthesis building block

ReferenceSame Category

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS110764-79-9

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

InChIKey

SARHDAQOZNKZCC-CJEGOSRCSA-N

SMILES

CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

Synonyms (16)
  • 5'-DMT-2'-OMe-Bz-A
  • Cytidine Impurity 54
  • DMT-OMe-Bz-rA
  • DMT-OMe-rA(Bz)