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Home/Compounds/Pharmaceutical Intermediate/5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
C40H49N4O9P
760.8 g/mol
Pharmaceutical Intermediate

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS110764-79-9
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite building block used in RNA synthesis. It is a protected, modified uridine derivative designed for solid-phase oligonucleotide assembly in laboratory and pharmaceutical research.

RNA synthesis phosphoramidite building blockLaboratory reagent for oligonucleotide production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.89

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-propyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)

CAS160526-54-5

research compound

StrongStructure SimilarSimilarity 0.89

5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite

CAS163759-97-5

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.87

5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS146954-75-8

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.86

5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS118362-03-1

pharmaceutical intermediate

ApplicationSame Use

2'-propargyl U amidite

CAS171486-62-7

pharmaceutical intermediate

ReferenceSame Category

N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS110782-31-5

pharmaceutical intermediate

ReferenceSame Category

5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-amine

CAS1108745-30-7

pharmaceutical intermediate

ReferenceSame Category

4-Chloro-3-fluorobenzonitrile

CAS110888-15-8

pharmaceutical intermediate

Identifiers
IUPAC Name

3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

UVUOJOLPNDCIHL-XKZJCBTISA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OC)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Synonyms (25)
  • 2'-OMe-U-CE-Phosphoramidite
  • Cytidine Impurity 15
  • Dmt-2'o-methyl-ru amidite