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Home/Compounds/Research Reagent/Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-propyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
C42H53N4O9P
788.9 g/mol
Research Reagent

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-propyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)

CAS160526-54-5
Category
Research Reagent
Compound Class
Other
Primary Use
Research Compound

This compound is a modified uridine phosphoramidite building block specifically designed for the solid-phase synthesis of RNA oligonucleotides. Its structure incorporates a 2'-O-propyl protection group, a 5'-O-(4,4'-dimethoxytrityl) (DMT) group, and a 3'-O-(diisopropylamino-2-cyanoethoxyphosphanyl) group, enabling its use as a key monomer in automated RNA synthesis.

RNA synthesis building blockAutomated oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 160526-54-5

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Related Compounds

StrongStructure SimilarSimilarity 0.91

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5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite

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StrongStructure SimilarSimilarity 0.89

5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

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Identifiers
IUPAC Name

3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-propoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

YUKSSAHYYXKOAN-CYSIDSPMSA-N

SMILES

CCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N

Synonyms (1)

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