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Home/Compounds/Research Reagent/DMT-2'-F-Bz-dA
C38H34FN5O6
675.7 g/mol
Research Reagent

DMT-2'-F-Bz-dA

CAS136834-21-4
Category
Research Reagent
Compound Class
Heterocycle
Primary Use
Research Compound

This compound is a modified nucleoside building block featuring a 2'-fluoro-2'-deoxyadenosine core with a benzamide-protected adenine base and a dimethoxytrityl protecting group at the 5'-hydroxyl. It is used primarily as a research reagent in the synthesis of oligonucleotides.

research reagent for modified oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 136834-21-4

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Related Compounds

SimilarStructure SimilarSimilarity 0.84

N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

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N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine

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N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine

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SimilarStructure SimilarSimilarity 0.73

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

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Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide

InChIKey

DDOOVEXTSRBCMU-VYUOYPLNSA-N

SMILES

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)F)O

Synonyms (15)
  • 5'-DMT-2'-F-Bz-dA
  • Cytidine Impurity 74
  • DMT-2'-F-Bz-A
  • DMT-2'-F-Bz-dA