C38H35N5O6
657.7 g/mol
Pharmaceutical IntermediateWarning
DMBTA
CAS64325-78-6EC264-776-4
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate
DMBTA is a protected nucleoside derivative used as a key building block in the chemical synthesis of oligonucleotides. Its structure features a deoxyadenosine core with a 5'-O-DMT (dimethoxytrityl) protecting group and an N6-benzoyl modification, which are standard for solid-phase DNA synthesis.
Protected nucleoside for oligonucleotide synthesisPharmaceutical intermediate in nucleoside chemistry
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 64325-78-6
Related Compounds
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SimilarStructure SimilarSimilarity 0.73
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
InChIKey
LPICNYATEWGYHI-WIHCDAFUSA-N
SMILES
COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)O
Synonyms (18)
- DMBTA
- Bz-DMT-dA