ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/5'-O-(4,4'-Dimethoxytrityl)uridine
C30H30N2O8
546.6 g/mol
Pharmaceutical Intermediate

5'-O-[bis(4-methoxyphenyl)phenylmethyl]uridine

CAS81246-79-9
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside derivative featuring a 5'-O-(4,4'-dimethoxytrityl) group attached to uridine. It is primarily used as a building block in the chemical synthesis of oligonucleotides, where the dimethoxytrityl group serves as a temporary protecting group for the 5'-hydroxyl during chain elongation.

Building block for oligonucleotide synthesisProtected nucleoside for DNA/RNA solid-phase synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 81246-79-9

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

StrongStructure SimilarSimilarity 0.85

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methyluridine

CAS103285-22-9

research compound

StrongStructure SimilarSimilarity 0.85

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorouridine

CAS146954-74-7

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.77

5'-O-DMT-2'-TBDMS-Uridine

CAS81246-80-2

research compound

SimilarStructure SimilarSimilarity 0.75

5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine

CAS2095417-73-3

research compound

ApplicationSame Use

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

CAS64325-78-6

pharmaceutical intermediate

ReferenceSame Category

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]adenosine

CAS81265-93-2

pharmaceutical intermediate

ReferenceSame Category

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine

CAS81279-39-2

pharmaceutical intermediate

ReferenceSame Category

N-[(1,1-Dimethylethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-D-alanine

CAS81306-93-6

pharmaceutical intermediate

Identifiers
IUPAC Name

1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione

InChIKey

PCFSNQYXXACUHM-YULOIDQLSA-N

SMILES

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CC(=O)NC5=O)O)O

Synonyms (12)
  • 5'-O-DMT-D-uridine
  • 5'-O-DMT-rU
  • 5'-O-DMT-uridine
  • DMT-rU