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Home/Compounds/Pharmaceutical Intermediate/5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorouridine
C30H29FN2O7
548.6 g/mol
Pharmaceutical Intermediate

5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorouridine

CAS146954-74-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a modified nucleoside building block featuring a protected ribofuranose core with a fluorine substitution and a uracil base. It is primarily used as a synthetic intermediate in pharmaceutical research for the preparation of modified oligonucleotides.

modified nucleoside building block for oligonucleotide synthesispharmaceutical intermediate for research use

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 146954-74-7

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Related Compounds

StrongStructure SimilarSimilarity 0.85

5'-O-(4,4'-Dimethoxytrityl)uridine

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pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.81

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methyluridine

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SimilarStructure SimilarSimilarity 0.74

5'-O-DMT-2'-TBDMS-Uridine

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SimilarStructure SimilarSimilarity 0.73

Triethylamine 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl)oxy)-4-oxobutanoate

CAS2294880-79-6

research compound

ReferenceSame Category

5'-O-(4,4-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

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Mirogabalin Impurities N75

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Dapagliflozin Impurity 9

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Identifiers
IUPAC Name

1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione

InChIKey

CSSFZSSZXOCCJB-YULOIDQLSA-N

SMILES

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CC(=O)NC5=O)F)O

Synonyms (19)
  • 2'-F-dU
  • 2'-Fluoro-5'-O-DMT-uridine