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Home/Compounds/Pharmaceutical Intermediate/N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methylcytidine
C33H35N3O8
601.6 g/mol
Pharmaceutical Intermediate

N-(1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

CAS199593-08-3
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside derivative used as an intermediate in the solid-phase synthesis of oligonucleotides. Its structure features a uridine base with an acetamide group and a 4,4′-dimethoxytrityl (DMT) protecting group on the 5′-hydroxyl, along with a 2′-O-methyl modification, making it suitable for RNA-based oligonucleotide assembly.

nucleoside intermediate for oligonucleotide synthesisresearch reagent for nucleic acid chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 199593-08-3

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Related Compounds

SimilarStructure SimilarSimilarity 0.85

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]cytidine

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SimilarStructure SimilarSimilarity 0.83

N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine

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SimilarStructure SimilarSimilarity 0.73

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N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

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pharmaceutical intermediate

ApplicationSame Use

N-(1-((1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

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N6-BENZOYL-2'-O-METHYL-ADENOSINE

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ReferenceSame Category

1-Bromo-4-chloro-2-fluorobenzene

CAS1996-29-8

pharmaceutical intermediate

ReferenceSame Category

4-[[[[6-[(Diethylamino)methyl]-2-naphthalenyl]methoxy]carbonyl]amino]benzoic acid

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pharmaceutical intermediate

Identifiers
IUPAC Name

N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChIKey

FINUHOJILDNELQ-PMFUCWTESA-N

SMILES

CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC

Synonyms (16)
  • Cytidine Impurity 60
  • DMT-OMe-Ac-rC
  • DMT-OMe-rC(Ac)