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Home/Compounds/Pharmaceutical Intermediate/N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine
C32H32FN3O7
589.6 g/mol
Pharmaceutical Intermediate

N-Acetyl-5'-o-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoroCytidine

CAS159414-98-9
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a fluorinated nucleoside intermediate featuring a protected hydroxyl group and an acetylated cytidine-like base. It is primarily used as a building block in the research-scale and commercial synthesis of modified nucleosides.

Pharmaceutical intermediate for nucleoside synthesisResearch compound for oligonucleotide development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.83

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methylcytidine

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SimilarStructure SimilarSimilarity 0.77

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]cytidine

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pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.73

N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

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ApplicationSame Use

((3aR,4R,6R,6aR)-2,2-Dimethyl-6-(2-oxo-4-(1H-1,2,4-triazol-1-yl)pyrimidin-1(2H)-yl)tetrahydro-2H-furo(3,4-d)(1,3)dioxol-4-yl)methyl 2-methylpropanoate

CAS2346620-54-8

pharmaceutical intermediate

ApplicationSame Use

Cytidine, N-benzoyl-2'-deoxy-5-methyl-

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pharmaceutical intermediate

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N-Benzoylcytidine

CAS13089-48-0

pharmaceutical intermediate

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5'-O-DMT-2'-O-TBDMS-Pseudouridine

CAS144429-56-1

pharmaceutical intermediate

ReferenceSame Category

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS159414-99-0

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChIKey

JIFNUYITABZZQS-PYYPWFDZSA-N

SMILES

CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)F

Synonyms (16)
  • 5'-DMT-2'-F-Ac-dC
  • 5'-O-DMT-N4-Ac-2'-F-dC
  • Cytidine Impurity 62
  • DMT-2'-FAc-C