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Home/Compounds/Pharmaceutical Intermediate/N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]cytidine
C38H47N3O8Si
701.9 g/mol
Pharmaceutical Intermediate

N-Acetyl-5'-O-(bis(4-methoxyphenyl)(phenyl)methyl)-2'-O-(tert-butyl(dimethyl)silyl)cytidine

CAS121058-85-3
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside derivative used as an intermediate in the chemical synthesis of oligonucleotides. It features a silyl protecting group and multiple aromatic rings, making it suitable for controlled assembly of nucleic acid sequences in laboratory research.

Building block in oligonucleotide synthesisNucleoside protecting group intermediate for research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.85

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methylcytidine

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SimilarStructure SimilarSimilarity 0.77

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ReferenceSame Category

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

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ReferenceSame Category

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ReferenceSame Category

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Referencesame scaffold

N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

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Identifiers
IUPAC Name

N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChIKey

ZFRWPAYPCFTQHK-HYGOWAQNSA-N

SMILES

CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)O[Si](C)(C)C(C)(C)C

Synonyms (15)
  • 5'-DMT-2'-TBDMS-Ac-rC
  • 5'-O-DMT-2'-O-TBDMS-Ac-rC
  • TBS-Ac-rC