Home/Compounds/Pharmaceutical Intermediate/Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
C47H60N7O10P
914 g/mol
Pharmaceutical IntermediateWarning
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS251647-55-9
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate
This compound is a protected nucleoside phosphoramidite building block used primarily in oligonucleotide synthesis. It is a chemically modified guanosine derivative with multiple protecting groups and a phosphoramidite functional group.
Protected building block for oligonucleotide synthesisPharmaceutical intermediate for nucleoside analog production
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 251647-55-9
Related Compounds
StrongStructure SimilarSimilarity 0.91
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StrongStructure SimilarSimilarity 0.89
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Safety Reference
Warning
H302Harmful if swallowed
Identifiers
IUPAC Name
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChIKey
LADCDGNEBIQAAU-SBCRAQIVSA-N
SMILES
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCOC
Synonyms (20)
- DMT-2'-O-MOE-G(iBu)-CEP
- DMT-2M-O-Me-rG(ib) amidite
- DMT-2mu-O-Me-rG(ib) amidite
- DMT-2|I-O-Me-rG(ib)amidite