ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 3'-CED
C60H86N7O9P
1080.3 g/mol
Pharmaceutical Intermediate

N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 3'-CED

CAS2382942-32-5
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a phosphoramidite building block specifically designed for oligonucleotide synthesis, featuring a hexadecyl chain for lipophilic properties. Its structure includes multiple protective groups for controlled assembly in solid-phase DNA/RNA synthesis.

phosphoramidite building block for oligonucleotide synthesisresearch reagent for nucleic acid chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 2382942-32-5

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

StrongStructure SimilarSimilarity 0.88

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS251647-55-9

pharmaceutical intermediate

StrongStructure SimilarSimilarity 0.86

2'-O-Propargyl g(iBu)-3'-phosphoramidite

CAS171486-61-6

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.83

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS144089-97-4

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.75

2'-dG(iBu)-2'-phosphoramidite

CAS157327-97-4

pharmaceutical intermediate

ApplicationSame Use

Methyl 16-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-3-yl]oxyhexadecanoate

CAS2642320-25-8

pharmaceutical intermediate

ApplicationSame Use

(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-(((dimethylamino)methylene)amino)-6-oxo-3H-purin-9(6H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS709641-79-2

pharmaceutical intermediate

ApplicationSame Use

1-(2,5-Anhydro-4-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-6-deoxy-alpha-L-mannofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS1197033-22-9

pharmaceutical intermediate

ReferenceSame Category

(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(hexadecyloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS2382942-35-8

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexadecoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChIKey

UOYPBRBOXKOJLE-ZGTMVWBUSA-N

SMILES

CCCCCCCCCCCCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)NC(=O)C(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N

Synonyms (7)

—