ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-6-oxo-1H-purin-2-yl]-2-phenylacetamide
C39H39ClN7O5P
752.2 g/mol
Pharmaceutical Intermediate

N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-6-oxo-1H-purin-2-yl]-2-phenylacetamide

CAS1044241-74-8
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected phosphoramidite reagent used as a pharmaceutical intermediate in the manufacturing of oligonucleotides. It features a purine base with dimethoxytrityl (DMT) and benzoyl protecting groups, along with a chloro(dimethylamino)phosphoryl moiety for coupling reactions.

Pharmaceutical intermediate for oligonucleotide synthesisBuilding block in solid-phase DNA/RNA synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 1044241-74-8

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

SimilarStructure SimilarSimilarity 0.82

((2S,6R)-6-(2-Isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

CAS956139-25-6

pharmaceutical intermediate

ApplicationSame Use

N4-Ac-C-(S)-GNA phosphoramidite

CAS1159174-80-7

pharmaceutical intermediate

ApplicationSame Use

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]purin-6-yl]benzamide

CAS136834-22-5

pharmaceutical intermediate

ApplicationSame Use

N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

CAS144089-96-3

pharmaceutical intermediate

ApplicationSame Use

5'-DMT-PseudoUridine

CAS144429-55-0

pharmaceutical intermediate

ReferenceSame Category

Benzyl (3R)-3-aminopiperidine-1-carboxylate

CAS1044560-96-4

pharmaceutical intermediate

ReferenceSame Category

2-Aminoethylmethylsulfone hydrochloride

CAS104458-24-4

pharmaceutical intermediate

ReferenceSame Category

Imidodicarbonic acid, 2-(3-nitro-2-pyridinyl)-, 1,3-bis(1,1-dimethylethyl) ester

CAS1044758-23-7

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-6-oxo-1H-purin-2-yl]-2-phenylacetamide

InChIKey

NURVOJDGJURYKG-BFXPVMCSSA-N

SMILES

CN(C)P(=O)(OC[C@@H]1CN(C[C@@H](O1)N2C=NC3=C2N=C(NC3=O)NC(=O)CC4=CC=CC=C4)C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)Cl