C13H18N2O2
234.29 g/mol
Pharmaceutical IntermediateDanger
(R)-1-Cbz-3-aminopiperidine
CAS1044560-96-4
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
(R)-1-Cbz-3-aminopiperidine is a chiral pharmaceutical intermediate featuring a piperidine ring with an amine group and a carbobenzyloxy (Cbz) protecting group. It is primarily used as a building block in the synthesis of active pharmaceutical ingredients, particularly in research and manufacturing settings.
Synthesis of cereblon E3 ligase modulators (IMiDs)Pharmaceutical intermediate for drug developmentLaboratory research compound
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Benzyl (3R)-3-aminopiperidine-1-carboxylate--hydrogen chloride (1/1)
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SimilarStructure SimilarSimilarity 0.85
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(R)-1-Cbz-3-Aminopyrrolidine hydrochloride
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SimilarStructure SimilarSimilarity 0.72
1-[(Benzyloxy)carbonyl]-3-piperidinecarboxylic acid
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pharmaceutical intermediate
ReferenceSame Category
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pharmaceutical intermediate
ReferenceSame Category
Imidodicarbonic acid, 2-(3-nitro-2-pyridinyl)-, 1,3-bis(1,1-dimethylethyl) ester
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pharmaceutical intermediate
ReferenceSame Category
(S)-3-Aminotetrahydrofuran tosylate
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pharmaceutical intermediate
Safety Reference
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
Identifiers
IUPAC Name
benzyl (3R)-3-aminopiperidine-1-carboxylate
InChIKey
PBFBPDLWODIXHK-GFCCVEGCSA-N
SMILES
C1C[C@H](CN(C1)C(=O)OCC2=CC=CC=C2)N
Synonyms (7)
- (R)-1-Cbz-3-aminopiperidine
- (r)-3-amino-1-cbz-piperidine
- (r)-n-cbz-3-amino-piperidine
Sourcing (R)-1-Cbz-3-aminopiperidine?
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