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Home/Compounds/Pharmaceutical Intermediate/5'-DMT-PseudoUridine
C30H30N2O8
546.6 g/mol
Pharmaceutical Intermediate

5'-DMT-PseudoUridine

CAS144429-55-0
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

5'-DMT-PseudoUridine is a chemically protected nucleoside used as a building block in the solid-phase synthesis of oligonucleotides. Its structure incorporates a 4,4'-dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl, enabling selective deprotection during chain elongation.

Building block for automated oligonucleotide synthesisIntermediate in the production of modified RNA and DNA sequences

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

5-[(2S,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-1H-pyrimidine-2,4-dione

InChIKey

VQCCPYGPORQHRE-CWTOASCOSA-N

SMILES

COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)C5=CNC(=O)NC5=O)O)O

Synonyms (2)
  • 5'-DMT-PseudoUridine