C34H33ClN6O7
673.1 g/mol
APIWarning
Neratinib maleate
CAS915942-22-2
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Neratinib maleate is the maleate salt form of neratinib, an orally available, irreversible inhibitor of the receptor tyrosine kinases HER2 and EGFR. It is used as an active pharmaceutical ingredient in the manufacturing of pharmaceutical products, targeting HER2- and EGFR-expressing tumor cells.
active pharmaceutical ingredient for pharmaceutical manufacturingresearch compound for HER2/EGFR inhibition studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 915942-22-2
Related Compounds
StrongSame Parent
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Referencesame scaffold
4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline
CAS848139-78-6
pharmaceutical raw material
Safety Reference
Warning
H302Harmful if swallowed
H319Causes serious eye irritation
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
(Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKey
VXZCUHNJXSIJIM-MEBGWEOYSA-N
SMILES
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C.C(=C\C(=O)O)\C(=O)O
Synonyms (11)
- 915942-22-2 (maleate)
- NERATINIB MALEATE ANHYDROUS
- Neratinib maleate
- Nerlynx
- Nerlynx (TN)
- hki-272 maleate