ChemAbout
© 2026 ChemAbout
Insights|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/API/Shr-1258 dimaleate
C40H39ClN6O11
815.2 g/mol
API

Pyrotinib dimaleate

CAS1397922-61-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Pyrotinib dimaleate is the dimaleate salt form of pyrotinib, an orally bioavailable dual kinase inhibitor targeting epidermal growth factor receptor (EGFR/HER-1) and human epidermal growth factor receptor 2 (HER-2). It functions by binding to and inhibiting both EGFR and HER2 receptor tyrosine kinases, thereby suppressing tumor growth and angiogenesis in EGFR/HER2-expressing tumor cells.

compound used in research as a dual EGFR/HER2 kinase inhibitorpharmaceutical raw material for oncology research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing or supplying this compound?

List your inventory or post a purchase request

CAS 1397922-61-0

List This Product
Sign in to publish supply information
Request This Product
Submit a request without registering

Related Compounds

StrongSame Parent

Pyrotinib

CAS1269662-73-8

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.73

Neratinib

CAS698387-09-6

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.73

Neratinib maleate

CAS915942-22-2

pharmaceutical raw material

ReferenceSame Category

1H-Purine-2,6-dione, 8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl-4,4,4-d3)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-; 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl-4,4,4-d3)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-p

CAS1398044-48-8

pharmaceutical raw material

ReferenceSame Category

(+/-)-Phenoxybenzamine-d5 HCl (benzyl-2,3,4,5,6-d5)

CAS1398065-71-8

pharmaceutical raw material

ReferenceSame Category

Rac Atomoxetine-d5 Hydrochloride

CAS1398065-95-6

pharmaceutical raw material

ReferenceSame Category

Urapidil-d3 (methoxy-d3)

CAS1398066-08-4

pharmaceutical raw material

Identifiers
IUPAC Name

bis((Z)-but-2-enedioic acid);(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide

InChIKey

KLHFGQSCVQPTIN-XUZAKNADSA-N

SMILES

CCOC1=C(C=C2C(=C(C=NC2=C1)C#N)NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)NC(=O)/C=C/[C@@H]5N(CCC5)C.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O

Synonyms (7)
  • Pyrotinib Maleate
  • Pyrotinib dimaleate
  • SHR-1258 dimaleate