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Home/Compounds/API/Shr-1258 dimaleate
C40H39ClN6O11
815.2 g/mol
API

Pyrotinib dimaleate

CAS1397922-61-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Pyrotinib dimaleate is the dimaleate salt form of pyrotinib, an orally bioavailable dual kinase inhibitor targeting epidermal growth factor receptor (EGFR/HER-1) and human epidermal growth factor receptor 2 (HER-2). It functions by binding to and inhibiting both EGFR and HER2 receptor tyrosine kinases, thereby suppressing tumor growth and angiogenesis in EGFR/HER2-expressing tumor cells.

compound used in research as a dual EGFR/HER2 kinase inhibitorpharmaceutical raw material for oncology research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Pyrotinib

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SimilarStructure SimilarSimilarity 0.73

Neratinib

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SimilarStructure SimilarSimilarity 0.73

Neratinib maleate

CAS915942-22-2

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Identifiers
IUPAC Name

bis((Z)-but-2-enedioic acid);(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide

InChIKey

KLHFGQSCVQPTIN-XUZAKNADSA-N

SMILES

CCOC1=C(C=C2C(=C(C=NC2=C1)C#N)NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)NC(=O)/C=C/[C@@H]5N(CCC5)C.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O

Synonyms (7)
  • Pyrotinib Maleate
  • Pyrotinib dimaleate
  • SHR-1258 dimaleate

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