C30H29ClN6O3
557 g/mol
APIDanger
Neratinib
CAS698387-09-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Neratinib is a quinoline compound with a cyano group, a 3-chloro-4-(2-pyridylmethoxy)anilino group, and other substituents. It functions as an antineoplastic agent and a tyrosine kinase inhibitor.
Pharmaceutical raw material for kinase inhibitor manufacturingResearch compound for HER-2 tyrosine kinase inhibition studiesP-glycoprotein inhibitor research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing or supplying this compound?
List your inventory or post a purchase request
CAS 698387-09-6
Related Compounds
StrongSame Parent
Neratinib maleate
CAS915942-22-2
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.73
Pyrotinib
CAS1269662-73-8
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.73
Shr-1258 dimaleate
CAS1397922-61-0
pharmaceutical raw material
ApplicationSame Use
Xl-228
CAS898280-07-4
pharmaceutical raw material
ApplicationSame Use
Wz-4002
CAS1213269-23-8
pharmaceutical raw material
ApplicationSame Use
Repotrectinib
CAS1802220-02-5
pharmaceutical raw material
ApplicationSame Use
Selitrectinib
CAS2097002-61-2
pharmaceutical raw material
ReferenceSame Category
Fusidic acid
CAS6990-06-3
pharmaceutical raw material
Safety Reference
Danger
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H360May damage fertility or the unborn child
Identifiers
IUPAC Name
(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKey
JWNPDZNEKVCWMY-VQHVLOKHSA-N
SMILES
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C
Synonyms (21)
- Neratinib (USAN/INN)
- 698387-09-6 (free base)
- NERATINIB [MART.]
- Neratinib
- Neratinib (HKI-272)
- Neratinib (Standard)
- Neratinib - Bio-X trade mark
- Nerlynx
- neratinibum