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Home/Compounds/API/(17S)-methylnaltrexone bromide
C21H26BrNO4
436.3 g/mol
API

Methylnaltrexone bromide, (17S)-

CAS916045-21-1
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Methylnaltrexone bromide, (17S)-, is a quaternary ammonium salt compound that acts as a peripheral mu-opioid receptor antagonist. It is a pharmaceutical raw material derived from naltrexone, characterized by a positively charged nitrogen atom that limits its ability to cross the blood-brain barrier.

Pharmaceutical raw material for opioid-induced constipation researchCompound used in peripheral opioid receptor antagonist manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(3S,4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one bromide

InChIKey

IFGIYSGOEZJNBE-LHJYHSJWSA-N

SMILES

C[N@+]1(CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O)CC6CC6.[Br-]

Synonyms (8)
  • (S)-Naltrexone methobromide
  • Naltrexone (S)-methobromide