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Home/Compounds/Pharmaceutical Intermediate/5'-O-(4,4'-dimethoxitrityl)-3'-O-(tert-butyldimethylsilyl)-1-methylpseudouridine
C37H46N2O8Si
674.9 g/mol
Pharmaceutical Intermediate

5'-O-(4,4'-dimethoxitrityl)-3'-O-(tert-butyldimethylsilyl)-1-methylpseudouridine

CAS875302-43-5
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside derivative used as an intermediate in the synthesis of modified nucleosides for pharmaceutical research. It features a thymine base with a silyl-protected hydroxyl and a dimethoxytrityl-protected primary alcohol, enabling selective chemical modifications.

Intermediate in modified nucleoside synthesisBuilding block for pharmaceutical research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.88

5'-O-(4,4'-Dimethoxitrityl)-2'-O-(tert-butyldimethylsilyl)-1-N-methylpseudouridine

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SimilarStructure SimilarSimilarity 0.79

5'-O-(4,4'-dimethoxitrityl)-1-N-methylpseudouridine

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SimilarStructure SimilarSimilarity 0.75

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Referencesame scaffold

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Identifiers
IUPAC Name

5-[(2S,3S,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione

InChIKey

DOMAILDWCRIGEQ-JDIHBLRXSA-N

SMILES

CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O)C2=CN(C(=O)NC2=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

Synonyms (3)

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