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Home/Compounds/Pharmaceutical Intermediate/5'-O-(4,4'-dimethoxitrityl)-1-N-methylpseudouridine
C31H32N2O8
560.6 g/mol
Pharmaceutical Intermediate

5'-O-(4,4'-dimethoxitrityl)-1-N-methylpseudouridine

CAS875302-39-9
Category
Pharmaceutical Intermediate
Compound Class
n.a
Primary Use
Pharmaceutical Intermediate

This compound is a protected nucleoside derivative used as an intermediate in the chemical synthesis of RNA. It features a modified uridine core with a dimethoxytrityl (DMT) protecting group and a methyl group on the pyrimidine ring, making it suitable for oligonucleotide assembly.

Pharmaceutical intermediate for RNA synthesisBuilding block for oligonucleotide manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.79

5'-O-(4,4'-Dimethoxitrityl)-2'-O-(tert-butyldimethylsilyl)-1-N-methylpseudouridine

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SimilarStructure SimilarSimilarity 0.79

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ReferenceSame Category

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ReferenceSame Category

5'-DMT-3'-O-TBDMS-N1-Me-Pseudouridine-CE-Phosphoramidite

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ReferenceSame Category

Secukinumab

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ReferenceSame Category

(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

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Referencesame scaffold

5'-DMT-PseudoUridine

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Identifiers
IUPAC Name

5-[(2S,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione

InChIKey

VSNLNQTWDOWQBD-HPQIJTKRSA-N

SMILES

CN1C=C(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)O

Synonyms (2)

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