This compound is a phosphoramidite building block used in the chemical synthesis of RNA oligonucleotides. It features a protected ribose backbone with a dimethoxytrityl (DMT) group and a silyl-protected hydroxyl, along with a phosphoramidite moiety for stepwise coupling during RNA assembly.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 875302-45-7
5'-DMT-3'-O-TBDMS-N1-Me-Pseudouridine-CE-Phosphoramidite
pharmaceutical intermediate
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
research compound
Secukinumab
pharmaceutical intermediate
(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one
pharmaceutical intermediate
(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid
pharmaceutical intermediate
7|A-Acetyloxy-7|A-[9-(dimethyl(tert-butylsilyloxy)nonyl]estr-4-en-3-one
pharmaceutical intermediate
2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite
research compound
5'-O-(4,4'-Dimethoxitrityl)-2'-O-(tert-butyldimethylsilyl)-1-N-methylpseudouridine
pharmaceutical intermediate
3-[[(2R,3R,4S,5S)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
ZDZLHJPETUXZJT-NSASEYFNSA-N
CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)C2=CN(C(=O)NC2=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC