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Home/Compounds/API/Regorafenib
C21H15ClF4N4O3
482.8 g/mol
API

Regorafenib

CAS755037-03-7
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Regorafenib is a synthetic compound studied as an active pharmaceutical ingredient, characterized by an aromatic, halogen-containing structure. Its crystalline forms and monohydrate have been investigated for structural properties relevant to pharmaceutical manufacturing.

anticancer research compoundanti-angiogenic agent in pharmaceutical developmentactive pharmaceutical ingredient for drug substance production

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Regorafenib monohydrate

CAS1019206-88-2

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.83

Sorafenib

CAS284461-73-0

Multikinase inhibitor for cancer research

SimilarStructure SimilarSimilarity 0.83

Sorafenib tosylate

CAS475207-59-1

pharmaceutical raw material

ReferenceSame Category

Flupirtine maleate

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pharmaceutical raw material

ReferenceSame Category

(R)-colchicine

CAS75520-89-7

pharmaceutical raw material

ReferenceSame Category

Ingenol mebutate

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pharmaceutical raw material

ReferenceSame Category

Fludarabine phosphate

CAS75607-67-9

pharmaceutical raw material

Referencesame scaffold

4-[4-[[[[2-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide

CAS1431697-81-2

pharmaceutical intermediate

Identifiers
IUPAC Name

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide

InChIKey

FNHKPVJBJVTLMP-UHFFFAOYSA-N

SMILES

CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F

Synonyms (21)
  • A1JCR
  • Regorafenib (USAN/INN)
  • BAY 73-4506
  • BAY-734506 monohydrate
  • BAY73-4506 hydrochloride
  • REGORAFENIB ANHYDROUS
  • Regorafenib
  • Regorafenib (BAY 73-4506)
  • Regorafenib (Standard)
  • Regorafenibum
  • Stivarga
  • Stivarga (TN)