C21H16ClF3N4O3
464.8 g/mol
OtherDanger
Sorafenib
CAS284461-73-0EC608-209-4
Category
Other
Compound Class
n.a
Primary Use
Multikinase inhibitor for cancer research
Sorafenib is a multikinase inhibitor studied for its role in cancer treatment. It is characterized as an aromatic, heterocyclic compound containing amide, ether, and halogen functional groups.
Antineoplastic agentsProtein kinase inhibitors
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Sorafenib tosylate
CAS475207-59-1
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.83
Regorafenib
CAS755037-03-7
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.83
Regorafenib monohydrate
CAS1019206-88-2
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.74
4-[4-[[[[2-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
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pharmaceutical intermediate
ReferenceSame Category
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Research intermediate
ReferenceSame Category
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Laboratory reagent
ReferenceSame Category
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Laboratory reagent for research
ReferenceSame Category
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Pharmaceutical intermediate or research compound
Safety Reference
Danger
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H402Harmful to aquatic life
H410Very toxic to aquatic life with long lasting effects
Customs Tariff Classification
The international HS code for Sorafenib (CAS 284461-73-0) is 2933.39.
HS code (international, 6-digit)
2933.39
EU CN code (8-digit)
2933 39 99
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
InChIKey
MLDQJTXFUGDVEO-UHFFFAOYSA-N
SMILES
CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
Synonyms (38)
- BAX
- Sorafenib (USAN/INN)
- 1uwh
- 284461-73-0 (free base)
- 3gcs
- 3heg
- 4asd
- BA4 43 9006
- BAY 43-9006
- BAY 43-9006; Sorafenib
- BAY 545 9085
- Hit compound, 8
- K00597a
- Nexavar (TN) (Bayer)
- SORAFENIB [MART.]
- Sorafenib
- Sorafenib (Base)
- Sorafenib (Nexavar)
- Sorafenib (Standard)
- Sorafenib - Bio-X trade mark
- Sorafenib free base
- Sorafenib, 4
- sorafenib tosilate hydrate
- sorafenibum
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