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Home/Compounds/API/Sorafenib tosylate
C28H24ClF3N4O6S
637 g/mol
APIDanger

Sorafenib tosylate

CAS475207-59-1EC641-758-8
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Sorafenib tosylate is a salt form of sorafenib, a kinase inhibitor compound used as an active pharmaceutical ingredient in the manufacture of certain anticancer medications.

pharmaceutical raw material for kinase inhibitor productioncompound used in the manufacturing of targeted cancer therapies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Sorafenib

CAS284461-73-0

Multikinase inhibitor for cancer research

SimilarStructure SimilarSimilarity 0.83

Regorafenib

CAS755037-03-7

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.83

Regorafenib monohydrate

CAS1019206-88-2

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.74

4-[4-[[[[2-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide

CAS1431697-81-2

pharmaceutical intermediate

ReferenceSame Category

Adw-742

CAS475488-23-4

pharmaceutical raw material

ReferenceSame Category

GSK 621659A

CAS475489-15-7

pharmaceutical raw material

ReferenceSame Category

NVP-AEW541

CAS475489-16-8

pharmaceutical raw material

ReferenceSame Category

Isotretinoin

CAS4759-48-2

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H302Harmful if swallowed
H332Harmful if inhaled
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Sorafenib tosylate (CAS 475207-59-1) is 2933.39.

HS code (international, 6-digit)

2933.39

EU CN code (8-digit)

2933 39 99

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide;4-methylbenzenesulfonic acid

InChIKey

IVDHYUQIDRJSTI-UHFFFAOYSA-N

SMILES

CC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

Synonyms (41)
  • Sorafenib tosylate (USAN)
  • 475207-59-1 (tosylate)
  • BAY 43-9006 tosylate
  • BAY 54-9085
  • BAY43-9006 mono-p-tosylate
  • Nexavar
  • Nexavar (TN)
  • Nexavar(R)
  • SORAFENIB TOSILATE [MART.]
  • Sorafenib (BAY-43-9006)?
  • Sorafenib (Nexavar)
  • Sorafenib CRS
  • Sorafenib Hemitosylate
  • Sorafenib tosilate
  • Sorafenib tosilate (JAN)
  • Sorafenib tosilate CRS
  • Sorafenib tosylate
  • Sorafenib tosylateBay 43-9006
  • orafenib tosylate

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