C21H17ClF4N4O4
500.8 g/mol
APIDanger
Regorafenib monohydrate
CAS1019206-88-2
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Regorafenib monohydrate is a multi-kinase inhibitor used as an active pharmaceutical ingredient. It is an oral compound that targets angiogenic, stromal, and oncogenic receptor tyrosine kinases, including dual inhibition of VEGFR2 and TIE2.
Pharmaceutical raw material for anti-angiogenic researchLaboratory reagent for kinase inhibition studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing Regorafenib monohydrate?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.
Related Compounds
StrongSame Parent
Regorafenib
CAS755037-03-7
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.83
Sorafenib
CAS284461-73-0
Multikinase inhibitor for cancer research
SimilarStructure SimilarSimilarity 0.83
Sorafenib tosylate
CAS475207-59-1
pharmaceutical raw material
ReferenceSame Category
Sulfaclozine
CAS102-65-8
pharmaceutical raw material
ReferenceSame Category
Benzamidenafil
CAS1020251-53-9
pharmaceutical raw material
ReferenceSame Category
3-{2-[4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl](²H₄)ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS1020719-55-4
pharmaceutical raw material
ReferenceSame Category
4-amino-2,3,5,6-tetradeuterio-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
CAS1020719-86-1
pharmaceutical raw material
Referencesame scaffold
4-[4-[[[[2-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
CAS1431697-81-2
pharmaceutical intermediate
Safety Reference
Danger
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate
InChIKey
ZOPOQLDXFHBOIH-UHFFFAOYSA-N
SMILES
CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O
Synonyms (16)
- BAY 73-4506 (monohydrate)
- Regorafenib hydrate
- Regorafenib hydrate (JAN)
- Regorafenib monohydrate CRS
- Stivarga (TN)
- regorafenib monohydrate
Sourcing Regorafenib monohydrate?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.