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Home/Compounds/Pharmaceutical Intermediate/Boc-L-glutamic acid 1-methyl ester
C11H19NO6
261.27 g/mol
Pharmaceutical IntermediateWarning

(4S)-4-{[(tert-butoxy)carbonyl]amino}-5-methoxy-5-oxopentanoic acid

CAS72086-72-7EC873-236-2
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a protected derivative of L-glutamic acid, featuring a tert-butoxycarbonyl (Boc) protecting group on the amino group and a methyl ester on one of the carboxyl groups. It is commonly used as an intermediate in solid-phase peptide synthesis.

Pharmaceutical intermediate for peptide synthesisReagent in research and manufacturing of peptides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.85

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(R)-N-Boc-glutamic acid-1,5-dimethyl ester

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SimilarStructure SimilarSimilarity 0.76

Boc-L-Glutamic acid

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Cbz-L-Glutamic acid 1-benzyl ester

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L-tert-Leucine methyl ester hydrochloride

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(4S)-5-methoxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid

InChIKey

ZAYAFKXUQMTLPL-ZETCQYMHSA-N

SMILES

CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OC

Synonyms (15)
  • BOC-GLU-OME
  • Boc-L-Glu-Ome
  • BocNH-Glu-OMe