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Home/Compounds/Pharmaceutical Intermediate/(R)-N-Boc-glutamic acid-1,5-dimethyl ester
C12H21NO6
275.3 g/mol
Pharmaceutical IntermediateWarning

Dimethyl N-(tert-butoxycarbonyl)-L-glutamate

CAS59279-60-6EC858-937-3
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

Dimethyl N-(tert-butoxycarbonyl)-L-glutamate is a Boc-protected amino acid derivative used as an intermediate in pharmaceutical manufacturing. It features a tert-butoxycarbonyl protecting group on the amino functionality and two ester groups, contributing to its role as a building block in peptide synthesis and drug development.

pharmaceutical intermediate for peptide synthesisresearch compound in medicinal chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.88

(S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate

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SimilarStructure SimilarSimilarity 0.77

Boc-L-glutamic acid 1-methyl ester

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SimilarStructure SimilarSimilarity 0.77

Boc-L-glutamic acid 5-methyl ester

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ApplicationSame Use

Ethyl N-{2-[(tert-butoxycarbonyl)amino]ethyl}glycinate--hydrogen chloride (1/1)

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(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid

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3-[[(1,1-Dimethylethoxy)carbonyl]amino]-L-alanine methyl ester

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ReferenceSame Category

Chloroiodomethane

CAS593-71-5

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

dimethyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate

InChIKey

QNSPKWUAZQIIGZ-QMMMGPOBSA-N

SMILES

CC(C)(C)OC(=O)N[C@@H](CCC(=O)OC)C(=O)OC

Synonyms (25)
  • Boc-Glu(OMe)-OMe
  • Boc-L-Glu(Ome)-Ome
  • Dimethyl N-Boc-L-glutamate
  • dimethyl Boc-L-glutamate
  • dimethyl Boc-glutamate