ChemAbout

ChemAbout is a B2B platform where chemical buyers and suppliers discover each other.

Post a purchase requestList your products (for suppliers)
© 2026 ChemAbout
Compound Index|Demand Board|Insights|Exhibitions|Compliance|Help Center|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/N-Boc-L-pyroglutamic acid
C10H15NO5
229.23 g/mol
Pharmaceutical IntermediateWarning

1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) ester, (2S)-

CAS53100-44-0EC258-362-2
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a Boc-protected derivative of L-pyroglutamic acid, commonly used as an intermediate in peptide synthesis. Its structure features a tert-butoxycarbonyl (Boc) protecting group and a stereocenter, making it suitable for building chiral peptide chains.

Boc-protected amino acid intermediateReagent for peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing this compound?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→

Related Compounds

SimilarStructure SimilarSimilarity 0.77

(S)-N-Boc-2-pyrrolidone-5-carboxylic acid tert-butyl ester

CAS91229-91-3

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.77

Boc-D-Pyroglutamic acid tere-butyl ester

CAS205524-47-6

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.73

Boc-L-Pyroglutamic acid methyl ester

CAS108963-96-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.73

Boc-D-pyroglutamic acid methyl ester

CAS128811-48-3

pharmaceutical intermediate

ApplicationSame Use

(R)-N-Boc-glutamic acid-1,5-dimethyl ester

CAS59279-60-6

pharmaceutical intermediate

ApplicationSame Use

N-Boc-4-Oxo-L-proline methyl ester

CAS102195-80-2

pharmaceutical intermediate

ApplicationSame Use

Ethyl N-{2-[(tert-butoxycarbonyl)amino]ethyl}glycinate--hydrogen chloride (1/1)

CAS347890-34-0

pharmaceutical intermediate

ApplicationSame Use

3-((tert-Butoxycarbonyl)amino)cyclobutanecarboxylic acid

CAS1008773-79-2

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-5-oxopyrrolidine-2-carboxylic acid

InChIKey

MJLQPFJGZTYCMH-LURJTMIESA-N

SMILES

CC(C)(C)OC(=O)N1[C@@H](CCC1=O)C(=O)O

Synonyms (25)
  • BOC-PYR-OH
  • Boc-L-Pyr-OH
  • Boc-L-pyroglutamic acid
  • Boc-pyroGlu-OH
  • Boc-pyroglutamic acid
  • N-Boc-5-oxo-L-proline
  • N-Boc-L-glutamic Acid Lactam
  • N-Boc-L-pyroglutamic acid
  • N-Boc-Pyr-OH
  • N-Boc-pyroglutamic acid

Sourcing this compound?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→