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Home/Compounds/Pharmaceutical Intermediate/Cbz-L-Glutamic acid 1-benzyl ester
C20H21NO6
371.4 g/mol
Pharmaceutical Intermediate

(4S)-5-(benzyloxy)-4-{[(benzyloxy)carbonyl]amino}-5-oxopentanoic acid

CAS3705-42-8
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a protected glutamic acid derivative featuring benzyl ester and benzyloxycarbonyl (Cbz) protective groups. It serves as a key building block in solid-phase peptide synthesis, enabling the incorporation of glutamic acid residues while preventing unwanted side reactions.

building block for peptide synthesispharmaceutical intermediate for manufacturing protected amino acids

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(4S)-5-oxo-5-phenylmethoxy-4-(phenylmethoxycarbonylamino)pentanoic acid

InChIKey

VWHKODOUMSMUAF-KRWDZBQOSA-N

SMILES

C1=CC=C(C=C1)COC(=O)[C@H](CCC(=O)O)NC(=O)OCC2=CC=CC=C2

Synonyms (19)
  • 1-Benzyl N-Cbz-L-glutamate
  • Linaclotide Impurity 18
  • Z-Glu-OBn
  • Z-Glu-OBzl
  • Z-L-Glu-OBzl