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Home/Compounds/Pharmaceutical Intermediate/N-[(Phenylmethoxy)carbonyl]-L-glutamic acid tert-butyl ester
C17H23NO6
337.4 g/mol
Pharmaceutical Intermediate

Z-glu-otbu

CAS5891-45-2EC858-743-9
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is an N-protected glutamic acid derivative used as a building block in solid-phase or solution-phase peptide synthesis. It features both a benzyloxycarbonyl (Cbz) protecting group on the amino terminus and a tert-butyl ester protecting group on the side-chain carboxyl, enabling selective deprotection during peptide chain assembly.

Peptide synthesis intermediateBuilding block for pharmaceutical research and development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.84

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Identifiers
IUPAC Name

(4S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-4-(phenylmethoxycarbonylamino)pentanoic acid

InChIKey

VJECGKAFPHEJQS-ZDUSSCGKSA-N

SMILES

CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1=CC=CC=C1

Synonyms (14)
  • Cbz-Glu-OtBu
  • Linaclotide Impurity 27
  • z-glu-otbu