ChemAbout

ChemAbout is a B2B platform where chemical buyers and suppliers discover each other.

Post a purchase requestList your products (for suppliers)
© 2026 ChemAbout
Compound Index|Demand Board|Insights|Exhibitions|Compliance|Help Center|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/N-[(Phenylmethoxy)carbonyl]-L-glutamic acid tert-butyl ester
C17H23NO6
337.4 g/mol
Pharmaceutical Intermediate

Z-glu-otbu

CAS5891-45-2EC858-743-9
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is an N-protected glutamic acid derivative used as a building block in solid-phase or solution-phase peptide synthesis. It features both a benzyloxycarbonyl (Cbz) protecting group on the amino terminus and a tert-butyl ester protecting group on the side-chain carboxyl, enabling selective deprotection during peptide chain assembly.

Peptide synthesis intermediateBuilding block for pharmaceutical research and development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing Z-glu-otbu?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→

Related Compounds

SimilarStructure SimilarSimilarity 0.84

5-benzyl 1-(tert-butyl) ((benzyloxy)carbonyl)-L-glutamate

CAS62457-19-6

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.82

Boc-D-glutamic acid 1-benzyl ester

CAS34404-30-3

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.76

Cbz-L-Glutamic acid 1-benzyl ester

CAS3705-42-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.72

N-Cbz-L-glutamic acid 5-tert-butyl ester

CAS3886-08-6

research compound

ApplicationSame Use

(S)-2-[(tert-Butoxycarbonyl)amino]-3-(benzyloxycarbonylamino)propionic acid

CAS65710-57-8

pharmaceutical intermediate

ApplicationSame Use

N-Benzyloxycarbonyl-D-aspartic acid

CAS78663-07-7

pharmaceutical intermediate

ApplicationSame Use

Boc-D-aspartic acid 4-benzyl ester

CAS51186-58-4

pharmaceutical intermediate

ApplicationSame Use

Fmoc-Glu(OtBu)-Phe-OH

CAS1122076-55-4

pharmaceutical intermediate

Related Reading

Therapeutic Peptides in 2026: This Year's Breakthroughs

2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

Read more
Identifiers
IUPAC Name

(4S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-4-(phenylmethoxycarbonylamino)pentanoic acid

InChIKey

VJECGKAFPHEJQS-ZDUSSCGKSA-N

SMILES

CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1=CC=CC=C1

Synonyms (14)
  • Cbz-Glu-OtBu
  • Linaclotide Impurity 27
  • z-glu-otbu

Sourcing Z-glu-otbu?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→