C17H23NO6
337.4 g/mol
Research ReagentWarning
5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate
CAS3886-08-6EC223-421-3
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound
This compound is a protected glutamic acid derivative, specifically a Cbz- and tert-butyl ester-protected amino acid used as a building block in peptide synthesis. It features benzyloxycarbonyl (Cbz) protection on the amino group and tert-butyl ester protection on both carboxyl groups, enabling selective deprotection during solid-phase or solution-phase peptide assembly.
Building block in solid-phase peptide synthesisIntermediate in the preparation of protected peptide fragments
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 3886-08-6
Related Compounds
SimilarStructure SimilarSimilarity 0.82
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Safety Reference
Warning
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-(phenylmethoxycarbonylamino)pentanoic acid
InChIKey
GLMODRZPPBZPPB-ZDUSSCGKSA-N
SMILES
CC(C)(C)OC(=O)CC[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1
Synonyms (21)
- Cbz-Glu(OBut)-OH
- Cbz-L-Glu(otBu)-OH
- Z-(L)Glu(OtBu)-OH
- Z-Glu(OBut)-OH
- Z-Glu(OtBu)-OH
- Z-Glu(OtBu)-OH, >=99.0% (TLC)