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Home/Compounds/Research Reagent/N-Cbz-L-glutamic acid 5-tert-butyl ester
C17H23NO6
337.4 g/mol
Research ReagentWarning

5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate

CAS3886-08-6EC223-421-3
Category
Research Reagent
Compound Class
Peptide
Primary Use
Research Compound

This compound is a protected glutamic acid derivative, specifically a Cbz- and tert-butyl ester-protected amino acid used as a building block in peptide synthesis. It features benzyloxycarbonyl (Cbz) protection on the amino group and tert-butyl ester protection on both carboxyl groups, enabling selective deprotection during solid-phase or solution-phase peptide assembly.

Building block in solid-phase peptide synthesisIntermediate in the preparation of protected peptide fragments

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate (CAS 3886-08-6) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-(phenylmethoxycarbonylamino)pentanoic acid

InChIKey

GLMODRZPPBZPPB-ZDUSSCGKSA-N

SMILES

CC(C)(C)OC(=O)CC[C@@H](C(=O)O)NC(=O)OCC1=CC=CC=C1

Synonyms (21)
  • Cbz-Glu(OBut)-OH
  • Cbz-L-Glu(otBu)-OH
  • Z-(L)Glu(OtBu)-OH
  • Z-Glu(OBut)-OH
  • Z-Glu(OtBu)-OH
  • Z-Glu(OtBu)-OH, >=99.0% (TLC)

Sourcing 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate?

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