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Home/Compounds/Pharmaceutical Intermediate/N-Boc-D-glutamic acid 1-(tert-butyl) ester
C14H25NO6
303.35 g/mol
Pharmaceutical IntermediateWarning

(4R)-5-(tert-butoxy)-4-{[(tert-butoxy)carbonyl]amino}-5-oxopentanoic acid

CAS73872-71-6EC870-683-5
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

N-tert-butoxycarbonyl-D-glutamic acid tert-butyl ester is a protected derivative of D-glutamic acid, commonly used as an intermediate in peptide synthesis. It features tert-butoxycarbonyl (Boc) and tert-butyl ester protecting groups, which facilitate selective deprotection during solid-phase or solution-phase peptide assembly.

Building block for peptide synthesisIntermediate in pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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ReferenceSame Category

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(4R)-5-[(2-methylpropan-2-yl)oxy]-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid

InChIKey

YMOYURYWGUWMFM-SECBINFHSA-N

SMILES

CC(C)(C)OC(=O)[C@@H](CCC(=O)O)NC(=O)OC(C)(C)C

Synonyms (8)
  • Boc-D-Glu-OtBu