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Home/Compounds/Pharmaceutical Intermediate/N,N'-Dibenzyloxycarbonyl-L-lysine
C22H26N2O6
414.5 g/mol
Pharmaceutical Intermediate

N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysine

CAS405-39-0
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected lysine derivative featuring two benzyloxycarbonyl (Cbz) protecting groups on the amino functions. It is primarily used as a building block in solid-phase peptide synthesis, allowing the selective incorporation of lysine residues with orthogonal protection.

Protected amino acid for peptide synthesisBuilding block for solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.80

N-Boc-N'-Cbz-L-lysine

CAS2389-45-9

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.80

N-Cbz-N'-Boc-L-lysine

CAS2389-60-8

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.76

N'-Fmoc-N-Cbz-L-Lysine

CAS86060-82-4

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.76

N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N2-[(phenylmethoxy)carbonyl]-L-lysine

CAS105751-18-6

pharmaceutical intermediate

ReferenceSame Category

Chloromethyl methyl carbonate

CAS40510-81-4

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ReferenceSame Category

(3R)-1,3-Piperazinedicarboxylic acid 3-methyl 1-(phenylmethyl) ester

CAS405175-79-3

pharmaceutical intermediate

ReferenceSame Category

(1R,3R)-3-aminocyclohexanol

CAS40525-77-7

pharmaceutical intermediate

ReferenceSame Category

6-Methyl-4-phenylchroman-2-one

CAS40546-94-9

pharmaceutical intermediate

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Customs Tariff Classification

The international HS code for N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysine (CAS 405-39-0) is 2924.29.

HS code (international, 6-digit)

2924.29

EU CN code (8-digit)

2924 29 70

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-2,6-bis(phenylmethoxycarbonylamino)hexanoic acid

InChIKey

BLZXFNUZFTZCFD-IBGZPJMESA-N

SMILES

C1=CC=C(C=C1)COC(=O)NCCCC[C@@H](C(=O)O)NC(=O)OCC2=CC=CC=C2

Synonyms (17)
  • Cbz-Lys(Cbz)-OH
  • N2,N6-Bis-Cbz-L-lysine
  • N2,N6-Dicarbobenzoxy-L-lysine
  • Z-L-Lys(Z)-OH
  • Z-Lys(Z)-OH
  • Z-Lys(Z)-OH, >=98.0% (TLC)

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