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Home/Compounds/Pharmaceutical Intermediate/N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N2-[(phenylmethoxy)carbonyl]-L-lysine
C29H30N2O6
502.6 g/mol
Pharmaceutical Intermediate

Z-Lys(Fmoc)-OH

CAS105751-18-6
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Z-Lys(Fmoc)-OH is a protected lysine derivative commonly used in solid-phase peptide synthesis. It features both a benzyloxycarbonyl (Cbz) protecting group on the alpha-amino group and a fluorenylmethyloxycarbonyl (Fmoc) protecting group on the lysine side chain, enabling selective deprotection strategies.

Protected building block for peptide synthesisIntermediate in the production of custom peptidesReagent for solid-phase peptide assembly

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 1.00

N'-Fmoc-N-Cbz-L-Lysine

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StrongStructure SimilarSimilarity 0.88

N,N'-Bis-Fmoc-L-lysine

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SimilarStructure SimilarSimilarity 0.76

Fmoc-N'-Acetyl-L-lysine

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SimilarStructure SimilarSimilarity 0.76

N,N'-Dibenzyloxycarbonyl-L-lysine

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N-Fmoc-N'-Boc-L-Lysine

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Sodium p-phenolsulfonate dihydrate

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Identifiers
IUPAC Name

(2S)-6-(9H-fluoren-9-ylmethoxycarbonylamino)-2-(phenylmethoxycarbonylamino)hexanoic acid

InChIKey

LNKKPRSYVVUBTR-SANMLTNESA-N

SMILES

C1=CC=C(C=C1)COC(=O)N[C@@H](CCCCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O

Synonyms (10)
  • Cbz-Lys(Fmoc)-OH
  • Z-Lys(Fmoc)-OH